Antioxidant, antimicrobial and cytotoxic bioassay of Mollugo oppositifolius L
Abstract
sensitivities were performed by disc diffusion method and serial tube dilution method was carried out to determine the minimum
inhibitory concentrations on some human pathogenic bacteria and fungi. For cytotoxicity test, brine shrimp lethality bioassay was conducted. Among the three crude extracts, MOEE produced more significant inhibition of DPPH (IC50; 27 μg/ml); MOPE produced highest zone of inhibition against Bacillus subtilis (16.67 mm) and Microsporum spp. (16.0 mm). On the other hand, MOME produced mild cytotoxicity as 50% and 90% mortality (LC50 and LC90) 8.0 μg/ml and 85.12 μg/ml.
Key words: Antioxidant, antimicrobial, cytotoxicity, Mollugo oppositifolius
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DOI: https://doi.org/10.22377/ijgp.v5i2.194
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