In vitro free radical scavenging potential of Hydroethanolic extract in the leaves of Annona muricata

Abstract

Objective: The present study was carried out to validate the free radical scavenging activity of hydroethanolic leaf extract of Annona muricata. Materials and Methods: The A. muricata leaves were evaluated for its scavenging activity against the free radicals such as 1-diphenyl-2-picrylhydrazyl, superoxide, nitric oxide, hydroxyl, and hydrogen peroxide. Results: The obtained results showed that hydroethanolic leaf extract of A. muricata possessed maximum scavenging activity of free radicals at a concentration of 250 µg/mL which was comparable to that of standard ascorbic acid. Conclusion: The observations suggest that the A. muricata leaf extract might serve as a potential source of natural antioxidant by providing significant protection against oxidative stress.