Antilithiatic effect of flowers of Jasminum Auriculatum Vahl

Yogendr Bahuguna, Mohan Singh Maniyari Rawat, Vijay Juyal, Vikas Gupta


The effect of oral administration of aqueous and alcohol extracts of Jasminum auriculatum Vahl (Oleaceae) flowers on
calcium oxalate nephrolithiasis has been studied in male albino rats. Ethylene glycol feeding resulted in hyperoxaluria as well
as increased renal excretion of calcium and phosphate. Supplementation with aqueous and alcohol extract of J. auriculatum flowers significantly reduced the elevated urinary oxalate, showing a regulatory action on endogenous oxalate synthesis. The increased deposition of stone forming constituents in the kidneys of calculogenic rats was significantly lowered by curative and preventive treatment using aqueous and alcohol extracts. The results indicate that the flowers of J. auriculatum are endowed with antiurolithiatic activity.
Key words: Ethylene glycol, flowers, hyperoxaluria, Jasminum auriculatum, nephrolithiasis

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