Prospective, non-interventional, uncontrolled, open-chart, pharmacoepidemiologic study of prescribing patterns for anti-diabetic drugs at tertiary care hospital in Erode

Radhika P.R, Nandha Kumar J., Chetan H. Borkhataria


The aim of this study is to determine current prescribing patterns for anti-diabetic drugs adopted by physicians in Erode. The
prospective, non interventional, uncontrolled, open-chart, pharmacoepidemiological study was conducted from January -2007 to April -2007 at a diabetic care centre having 350 diabetic patients. The pattern of prescribing anti-diabetic drugs was recorded along with glycosylated haemoglobin levels, total cholesterol, high-density lipoprotein, low-density lipoprotein, very low-density lipoprotein and triglycerides in insulin-dependent diabetes mellitus and non-insulin-dependent diabetes mellitus patients and the values were observed. The prescribing pattern of the oral anti-diabetic drugs shows that out of the various oral anti-diabetic drugs’ available, drugs from only two groups were prescribed. Sulphonylureas, biguanides and combination therapy accounts for 31.43%, 20.28% and 33.71% of prescriptions, respectively, while insulin alone and with OAD’s accounts for 6.28% and 8.29% prescriptions, respectively. Overall,
prescribing trend is away from monotherapy with insulin and sulphonylureas and towards combination therapies.
Key words: Diabetes mellitus, oral anti-diabetic drugs, demographic profile, pharmacoepidemiologic

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