Isolation of galangogalloside from rhizomes of Alpinia galanga

Shivkanya Jaju, Nitin Indurwade, Dinesh Sakarkar, Neeraj Fuloria, Mohamad Al

Abstract


Alpinia galanga commonly known as Kulingen. Plant is selected for isolation of newer constituents responsible various therapeutic
activities like Antidiabetic and anti-inflammatory activities. The purpose of present study to isolate new phenolic glycoside from Alpinia galanga rhizomes. Methanolic extract of Alpinia galanga was column chromatographed and eluted with ethyl acetate-methanol (9:1) to isolate compound AG 13, Galangogalloside. New structure of Galangogalloside was interpreted by various spectral techniques (UV, IR, 1HNMR, 13CNMR, and MS). Chemical investigation of the methanolic extract of the rhizomes of Alpinia galanga furnished new gallic acid glycoside (Galangogalloside). New gallic acid glycoside isolated from medicinal plant or synthetic source for the first time.
Key words: AG 13, Alpinia galanga, galangogalloside, gallic acid glycoside, methanolic extract

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References


Kirtikar KR, Basu BD. Indian medicinal plants. Deraduhun

International Book Distributor; 1996. p. 2445.

Asolkar LV, Kakkar KK, Chakre OJ. Second Supplement to

“Glossary of Indian Medical Plants with active principles

Part – I (A-K). National institute of science communication.CSIR

publication;1992. p. 50-1.

Chadha YR. The Wealth of India (Raw materials). Vol. 1. Revised ed.

New Delhi: Council of Scientific and Industrial Research; 2003. p. 196.

Rastogi RP. Mehrotra BN.Compendium of Indian Medicinal

plants- 1970-1979. Vol 2. New Delhi: National institute of science

communication and CSIR; 2006. p. 33.

Janssen AM, Scheffer JC. Acetoxychavicol acetate, an antifungal

component of Alpinia galanga. Planta Med 1985;6:507-11.

Jirawan O, Tomoko S. Antimicrobial properties and action of galanga

(Alpinia galanga Linn.) on Staphylococcus aureus. LWT-Food and

Science Technology 2006;39:1214-20.

Matsuda H, Morikawa. Gastro protective effects of phenyl

propanoids from the rhizomes of Alpinia galanga in rats:

Structural requirements and mode of action. European Journal

of Pharmacology 2005;471:59-67.




DOI: http://dx.doi.org/10.22377/ijgp.v3i2.71

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