Comparative pharmaceutical standardization of Nimba (Azadirachta indica A. Juss) Kshara prepared from Nimba Kashtha (Trunk Wood) and Nimba Kandatwak (Trunk Bark)

Abstract

Introduction: Kshara Kalpana is an alkaline, water-soluble Ayurvedic preparation known for its therapeutic efficacy in the management of various diseases, both internally and externally. Classical texts such as Rasa Tarangini mention Nimba Kashtha (NK) (trunk wood) for Nimba Kshara preparation; however, its harvesting may be environmentally undesirable. This study aimed to develop and validate a standard manufacturing procedure (SMP) for Nimba Kshara and compare NK and Nimba Kandatwak (trunk bark) with respect to pharmaceutical yield and process reproducibility. M