Wound-healing potential of aqueous and ethanolic extracts of apamarga leaves

Article Sidebar

PDF
DOI: https://doi.org/10.22377/ijgp.v5i1.167

Main Article Content

P. K. Ghosh
V. B. Gupta
M. S. Rathore
Iqbal Hussain

Abstract

The present research work was aimed at exploring the wound-healing activity of alcoholic and an aqueous Achyranthes aspera Linn (apamarga) leaf extract. Leaf extracts (aqueous and ethanolic) were examined for its wound-healing activity in the form of ointment (1% w/w) in Excision model and Incision model in rats. The evaluation was made in terms of wound contractibility and wound closure time. A. aspera Linn leaf extract showed significant (P<0.001) wound-healing activity when compared with control and was as effective as soframycin (standard cream for comparison). The wound-healing potential of ethanolic extract was slightly more compared with aqueous extract. The present study showed the wound-healing potential of apamarga leaves.
Key words: Apamarga, extract, wound

Downloads

Download data is not yet available.

Article Details

Issue

Vol. 5 No. 1 (2011): Jan-Mar

Section

Articles

References

Tahiliani P, Kar A. Achyranthes aspera elevated thyroid hormone

level and decreases hepatic lipid peroxidation in male rats. J

Ethnopharmacol 2000;71:527-32.

Pakrashi A. Abortifacient principle of Achyranthes aspera Linn.

Indian J Exp. 1977;15:856-8.

Verma DK, Singh SK, Tripathi VA. Rare antibacterial activity of

Achyranthes aspera Linn. Indian Drug 1997;34:32-5.

Rao YV, Chakrabarti R. Dietary incorporation of Achyranthes aspera

seed influences the immunity of common carp cyprinus carpio.

Indian J Animal Sci 2005;75:1097-102.

Chakraborty A, Brantner A, Mukainaka T, Nobukuni Y, Kuchide

M, Konoshima T, et al. Cancer chemopreventive activity of

Achyranthes aspera leaves on Epstein-Barr virus activation

and two-stage mouse skin carcinogenesis. Cancer Lett 2002;

:1-5.

Gokhale AB, Damre AS, Kulkarni KR, Saraf MN. Preliminary

evaluation of anti-inflammatory and anti-arthritic activity of S.

lappa, A. speciosa and A. aspera. Phytomedicine (Jena) 2002;9:

-7.

Kokate CK. Practical pharmacognosy. 4th ed. New Delhi: Vallabh

Prakasan; 2001. p. 108-10,123-4.

Mukherjee PK. Quality Control of Herbal Drugs. New Delhi:

Business Horizons; 1st ed. 2002.