Gas chromatography-mass spectroscopy analysis of bioactive compounds in the whole plant parts of ethanolic extract of Asclepias Curassavica L.

Dr. Anju Dhiman

Abstract


Objective: The present study was carried out to cultivate Asclepias curassavica and explore the phytoconstituents of ethanolic extract of A. curassavica whole part using gas chromatography-mass spectroscopy (GC-MS). This research may be useful for constituent(s)-based pharmacological activity. Materials and Methods: 5 g of powdered plant material was taken in a spotless, level container and soaked in 80 ml of ethanol, and extraction was done by hot extraction method. The glass container with extract was sealed and kept aside for few hours. It was then filtered through Whatman filter paper No.42. Ethanolic extract of A. curassavica was further undertaken for GC-MS analysis. Result: The ethanolic extract of the whole plant of A. curassavica revealed the presence of 49 diverse phytochemical compounds. Several of these phytoconstituents are reported to possess pharmacological potential. Conclusion: A. curassavica L. has been successfully cultivated, authenticated, and used for the identification of its organic chemical components by GC-MS. Pesticide residues may have an adverse effect on the food chain, and the concentration should be within permissible range for safe human consumption of any herbal drug product. A. curassavica has been observed as a tremendous source of many important phytochemicals, especially glycosidal, alkaloids, steroidal, and terpenoidal compounds. There were no pesticidal residues found in the tested plant drug. Therefore, it may be explored for the production of natural medicinal formulations in pharmaceutical drug industries including anticancer drugs, antibacterial, antimicrobial, antiasthmatics, urine acidifiers, and antimicrobial on account of its potential antioxidant activity.

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DOI: http://dx.doi.org/10.22377/ijgp.v12i02.1840

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