In vitro free radical scavenging activity of hydroethanolic leaf extract of Ixora macrothyrsa (Tejism. and Binn.)

Dr. D. Victor Arokia Doss

Abstract


Objective: The present study aimed to evaluate the free radical scavenging activity of hydroethanolic leaf extract of Ixora macrothyrsa (Tejism. and Binn.). Materials and Methods: The hydroethanolic leaf extract of I. macrothyrsa was analyzed for free radical scavenging assay, namely 1-diphenyl-2-picrylhydrazyl (DPPH), hydroxyl radical, hydrogen peroxide (H2O2), and nitric oxide (NO) scavenging activity. Results: The hydroethanolic leaf extract of I. macrothyrsa was shown to scavenge DPPH, hydroxyl, H2O2, and NO radicals dose dependently with an IC50 value of 405.36, 306.57, 351.46, and 612.76 μg/mL, respectively. Conclusion: The results suggest that I. macrothyrsa has a promising antioxidant activity and could serve as a potential source of natural antioxidant.

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DOI: http://dx.doi.org/10.22377/ijgp.v12i04.2204

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