A review on Bacopa monniera: Current research and future prospects

Kashmira J. Gohil, Jagruti A. Patel

Abstract


In recent times, the use of herbal products has increased tremendously in the western world as well as in developed countries. Lately, one of the outstandingly important medicinal plants, widely used therapeutically in the orient and becoming increasingly popular in the west is Bacopa monniera, a well-known nootropic. The present review summarizes our current knowledge of pharmacological actions, preclinical and clinical studies, major bioactives, reported mechanisms of actions, clinical efficacy, safety and the possibility of interactions of the herb with the conventional drugs. Simultaneously, research updates as well as avenues for further research are
also mentioned concerning the plant.
Key words: Bacopa monniera, neurotonics, clinical studies, herb-drug interactions, preclinical studies

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References


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Khan R, Krishnakumar A, Paulose CS. Decreased glutamate

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of pilocarpine-induced epileptic rats: Neuroprotective role of

Bacopa monnieri extract. Epilepsy and Behav 2008;12:54-60.

Hota SK, Barhwal K, Baitharu I, Prasad D, Singh S, Ilavazhagan

G. Bacopa monniera leaf extract ameliorates hypobaric hypoxia

induced spatial memory impairment. Neurobiology of Disease

;34:23-39.

Singh A, Singh SK. Evaluation of antifertality potential of brahmi

in male mouse. Contraception 2009;79:71-9.

Prasad S, Kashyap RS, Deopujari JY, Purohit HJ, Taori GM,

Daginawala HF. Effect of Fagonia Arabica (Dhamasa) on in vitro

thrombolysis. BMC Compl Alt Med 2007;7:36.

Izzo AA, Ernst E. Interactions between herbal medicines and

prescribed drugs: A systematic review. Drugs 2001;61:2163-75.

Gohil KJ, Patel JA. Herb-drug interactions: A review and study

based on assessment of clinical case reports in literature. Ind J

Pharmacol 2007;39:129-39.




DOI: http://dx.doi.org/10.22377/ijgp.v4i1.111

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