Antibacterial evaluation of Sapindus emarginatus Vahl leaf in in-vitro conditions

Yogeshkumar Vaghasiya, Rathish Nair, Sumitra Chanda


The emergence of antibiotic resistant bacterial strains is a growing problem and is an important concern for patients, physicians,healthcare managers and policymakers as it results in poorer health and economic outcomes. This has led to an urgent global call for new antimicrobial drugs, particularly from natural resources. In the present study, antibacterial evaluation of aqueous, 1, 4-dioxan, methanol and acetone extracts of Sapindus emarginatus Vahl leaf was studied against 6 medically important bacterial strains. Antibacterial assay was performed by agar well diffusion method. Gentamicin (5mg/10ml) was used as standard antibiotic for comparison. Dioxan extract exhibited potential antibacterial activity
Key words: Agar well diffusion method, antibacterial evaluation, Sapindus emarginatus

Full Text:



Cowan MM. Plant products as antimicrobial agents. Clin Microbiol

Rev 1999;12:564-82.

Iwu MW, Duncan AR, Okunji CO. New antimicrobials of plant

origin. In: Janick J, editor Perspectives on New Crops and New

Uses. Alexandria VA: ASHS Press; 1999; p. 457.

Bhavnani SM, Ballow CH. New agents for Gram positive bacteria.

Curr Opin Microbiol 2000;3:528-34.

Mothana RA, Lindequist U. Antimicrobial activity of some

medicinal plants of the island Soqotra. J Ethnopharmacol


Vaghasiya Y, Nair R, Baluja S, Chanda S. Antibacterial and

preliminary phytochemical analysis of Eucalyptus citriodora Hk

leaf. Nat Prod Res 2008;22:754-62.

Perez C, Paul M, Bazerque P. An antibiotic assay by the agar well

diffusion method. Acta Biol Med Exp 1990;15:113-5.

Parekh J, Chanda S. In vitro antimicrobial activity and phytochemical

analysis of some Indian medicinal plants. Turk J Biol 2007;31:53-8.

Nair R, Kalariya T, Chanda S. Antibacterial activity of some

selected Indian medicinal flora. Turk J Biol 2005;29:41-7.



  • There are currently no refbacks.