Preliminary phytochemical and antibacterial screening of crude extract of the leaf of Adhatoda vasica. L

A. Karthikeyan, V. Shanthi, A. Nagasathaya


Preliminary phytochemical and antibacterial investigations were carried out of the crude extracts obtained from the leaf of Adhatoda vasica, using solvents of varied polarity. The presence of phenols, tannins, alkaloids, anthraquinones, saponins, flavanoids, aminoacids and reducing sugars was indicated by the tests conducted. The effect of ethanol, petroleum ether and water extracts were tested on Staphylococcus aureus, Staphylococcus epidermidis, Bacillus subtilis, Enterococcus faecalis, Escherichia coli, Pseudomonas aeroginosa, Proteus vulgaris, Klesiella pneumoniae and Candida albicans. The minimum inhibitory concentration of the crude extracts was determined for various organisms.
Key words: Adhatoda vasica, antibacterial activity, minimum inhibitory concentration

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