A clinical study of Vamana Karma with Madanaphala Kashaya Yoga through oral route and Madanaphala Ghreya Yoga through nasal routein the management of Ekakushtha (Psoriasis)

Abstract

Background: In Ayurveda, the word “Twacha” or “Charma” used for skin. Skin is considered one of the most important parts of the body. Skin is a link between internal and external environment and is also the seat of complexion, which maintains beauty and personality. Any disorder which affects the skin needs primary attention as it reflects the pathology inside the body and can cause physical, emotional, and socioeconomic embarrassment in the society. All the skin diseases in Ayurveda have been discussed under the broad headings of “Kushtha”. There are two types of Kushtha described in Ayurveda classics –Mahakushthaand Kshudrakushtha. Ekakushtha, a type of Kshudrakushtha characterized by Aswedanam (Absence of Perspiration), Mahavastu (Extensive localization), Matsyashakalopam (resembles the scales of fish). The signs and symptoms of Ekakushtha bear similarities to “Psoriasis” in modern medicine. Modern medical science treats Psoriasis with PUVA, corticosteroids, etc. However, these therapies give serious side effects such as hepatic and nephrotoxicity and bone marrow depression. For the management of Ekakushtha, Ayurveda offers a range of treatment approaches, with Panchakarma being considered the most effective. Panchakarma aims to address the root causes of the disease and enhance overall well-being. Vamana Karma, which is one among Panchkarmais used mainly for detoxification purpose, which eliminates the morbid Kapha dosha through oral route. Aim: The aim of the study was to analyze the comparative efficacy of Vamana with “MadanaphalaKashaya Yoga” through oral route and “MadanaphalaGhreya Yoga” through nasal route for Shodhana karma on affected area of skin in the management of Ekakushtha(Psoriasis). Materials and Methods: A research study was carried out on 30 patients with Ekakushtha, they were divided into two groups. These groups received treatment, followed by a follow-up evaluation conducted on the 16th day, 30th day, 45th day, and 60th days of treatment. In both groups, Deepana-Pachana was given with PanchkolaChurna and Snehapana was given with Go-Ghrita.In Group A Vamana was conducted by Madanaphala Kashaya Yoga, which is composed of Madanaphala, Yahstimadhu, Saindhava, and Madhu. In Group B, Vamana was conducted by Madanaphala Ghreya Yoga, which was composed of Madanaphala, Yashtimadhu, Saindhava, Madhu. Statistical Analysis: The results were statistically interpreted using different tests such as Wilcoxon signed-rank test, Mann–Whitney U test, Paired t-test, and Unpaired t-test to assess the statistical significance. Results: The study’s results indicated that Vamana Karma administered to Group A showed greater effectiveness in Aswedanam, Mahavastu, Matsyashakalopam, Rukshata, Varna, Kandu, Vedana, and PASI Score. Conclusions: Vamana Karma with Madanaphala Kashaya Yoga through oral route is more effective than MadanaphalaGhreya Yoga through nasal route in the management of Ekakushtha (Psoriasis).