Preparation and characterization of microspheres of ivabradine hydrochloride using natural, semi-synthetic, and synthetic polymers

Abstract

The present work was aimed to the development of controlled release formulations of esomeprazole and
dexlansoprazole to improve bioavailability. Both esomeprazole and dexlansoprazole are the proton-pump
inhibitor that suppresses gastric acid secretion by specific inhibition of the H+/K+-ATPase in the gastric parietal
cell. By acting specifically on the proton pump, esomeprazole and dexlansoprazole block the final step in acid
production, thus reducing gastric acidity.