Jawarish jalinoos: A polyherbal unani formulation for gastrointestinal disorders

Abstract

Introduction: Murakkab drugs of Unani medicine has been an important aspect of disease treatment since antiquity. Physicians prepared different formulations for various diseases. Jawarish Jalinoos is an Unani polyherbal formulation listed under the Majooniath category in the National Formulary of Unani Medicine, Part-I. It has a long history of traditional use for the management of several disorders related to gastrointestinal, cardiac, kidney, metabolism, and general health. The present study examined the effects of Jawarish Jalinoos in gastrointestinal and other disorders. Materials and Methods: Empirical searches were conducted on the medicinal plant via significant search engines such as Google Scholar, Scopus, PubMed, Microsoft academic, and Web of Science from inception up to July 2021. Besides, references from classical Unani literature and books, non-English journals were also included. Results: The ingredients of Jawarish Jalinoos contain, almost all, more or less, essential oils and their essential oil value should give a reliable therapeutic index. Its ingredients contain α- pinene, β- pinene, limonene, jatamansone, α-terpinyl acetate, eugenol, linalool, coumarin, gingerols, monoterpenes, sesquiterpenes, shogaols, etc., which possesses potent antimicrobial, anti-inflammatory, gastroprotective, neuroprotective, and antioxidant properties. Discussion and Conclusion: Till now, not a single study has been done on its pharmacological properties. According to different Unani Qarabadeen’s (Pharmacopoeias) this formulation is used in various ailments such as Zo’f-ī -Azae-Raeesa (weakness of the principle organs such as brain, heart, and liver), Zo’f-ī-mi’da (stomach weakness), Nafakh-ī-Shikam (flatulence), Khafqān (palpitation), Haemorrhoids, Tinea, Niqras (Gout), Sang-ī-Gurdā (Renal calculus), Sang-ī-Mathānā (Vesicular calculus), but scientific studies and clinical trials are needed on this compound formulation to ensure its scientific validation.