A preliminary pharmacognostical and pharmaceutical assay of Yastimadhu granules

Srihari Sheshagiri, Harisha Channappa Rudrappa, Vinay Shukla, Kalpana Shanthibhai Patel, Rajagopala Shrikrishna


Aim: Yastimadhu (Glycyrrhizha glabra Linn.) of Fabaceae family is one of the most commonly used herb in various Ayurvedic
preparations with its vivid actions on various systems. It is also used as a flavouring agent and taste corrigent in pharmaceutical as well as confectionery industries. In a study conducted to evaluate the role of Yastimadhu in enhancing intellect and memory of school going children, the drug was used in the form of granules so ask to mask the issue of palatability. Pharmacognostical and physico-chemical properties were explored to assess the genuine nature of the raw drug in this new formulation after it underwent the pharmaceutical
procedure. Materials and Methods: The present study provides the details of preparation of granules and methods employed in
pharmacognostical and physic-chemical qualities. Results: The results obtained revealed that the genuine properties of raw drug
did not change even after it underwent the pharmaceutical procedure into a new form which was easily palatable. Conclusion: As the drug possesses multiple actions and qualities, the new form would be of potential benefit to all age group of patients with issue of palatability. This study can also be used as a reference for further quality-control researches.
Key words: Yastimadhu (Glycyrrhiza glabra Linn.), pharmacognosy, physico-chemical analysis

Full Text:



Joy PP, Thomas J, Samuel M, Skaria BP. Medicinal Plants.

Agricultural University: Thrissur Dist, Kerala, India: Aromatic

and Medicinal Plants Research Station; 1998. p. 42-3

The Indian pharmaceutical codex. Vol. I. Indigenous drugs.

New Delhi: Council of Scientific & Industrial Research; 1953.

p. 112-3

Ghazanfar SA. Handbook of Arabian medicinal plants. Boca Raton,

FL: CRC Press; 1994. p. 110-1

Chin WY, Keng H. An illustrated dictionary of Chinese medicinal

herbs. Singapore: CRCS Publications; 1992

Bradley PR, editor. British herbal compendium, Vol. 1.

Bournemouth: British Herbal Medicine Association; 1992. p. 145-8

Hikino H. Recent research on Oriental medicinal plants. In:

Wagner H, Hikino H, Farnsworth NR, editors. Economic and

medicinal plant research. Vol.1. London: Academic Press; 1985.

p. 53-85

Takagi K, Harada M. Pharmacological studies on herb Peony root.

III. Effects of peoniflorin on circulatory and respiration system and

isolated organs. Yakugaku Zasshi 1969; 89: 893-6

Wrocinski, T. Determination of the activity of spasmolytic drugs

with reference to the papaverine standard. Biuletyn Instytutu

Roslin Leczniczych 1960; 6: 236

Shihata, I. M.; Elghamry, M. I. Experimental studies on the effect

of Glycyrrhiza glabra, Planta Med 1963; 11: 37-43

Dehpour AR, Zolfaghari ME, Samadian T, Kobarfard F, Faizi M,

Assari M. Antiulcer activities of liquorice and its derivatives in

experimental gastric lesion induced by ibuprofen in rats. Int J

Pharm 1995; 119: 133-8

Akram M, Shahab‑Uddin, Ahmed A, Usmanghani K, Hannan A,

Mohiuddin E, et al. Glycyrrhiza glabra L. (Medicinal uses), Journal

of Medicinal Plants Research (JMPR), 30th October 2011; 5: 5658-61.

ISSN 1996-0875

The Ayurvedic Pharmacopoeia of India, Part‑ I, Volume – I,

Government of India, Ministry of Health and Family Welfare.

Department of Ayush; New Delhi, p. 168‑9

WHO monographs on selected medicinal plants. Vol. 1, WHO

Library Cataloguing in Publication Data, WHO, Geneva 1999 ISBN

4 154517 8 (NLM Classification: QV 766)

Srikanta Murthy KR. Sarangadhara Samhitha‑ A treatise on

Ayurveda. 6th ed. Varanasi: Chaukhambha orentalia; 2006. p. 84

Wallis TE. A text book of Pharmacognosy, Reprinted edition.

London: Churchill Livingstone; 1967. p. 578‑617

Harborne JB. Phytochemical Methods, A Guide to Modern

Techniques of Plant Analysis. Harborne JB, eds. 2nd ed, Chapman

and Hall, London, 1984; p. 196

Paech K, Tracey MV. Modren methods of plant analysis, Vierter

band. In: Cromwell BT, editor. Vol. IV. Berlin: Springer-Verlac;

p. 370

Reich E, Blatter A, Meier B. TLC for the analysis of herbal drugs.

A critical review of the status and proposal for improvement of

Monographs, Switzerland, European Directorate for the Quality

of Medicines and healthcare, Scientific Note, Pharmeuropa 15.3,

July 2003. p. 424-30

“Quality standards of Indian medicinal plants”, Vol. 9. New Delhi:

Medicinal Plants Unit, Indian Council of Medical Research; 2011.

p. 176-83

DOI: https://doi.org/10.22377/ijgp.v6i2.250


  • There are currently no refbacks.