Isolation and characterisation of Cardiospermum halicacabum mucilage

X. Fatima Grace, S. Latha, S. Shanthi, S. Seethalakshmi, D. Chamundeeswari, P. K. Manna

Abstract


Cardiospermum halicacabum is an edible plant rich in mucilage, which belongs to the family Sapindaceae. Although the plant has
been used traditionally, there is no report on isolation and characterisation of mucilage from C. halicacabum. The present work was aimed to isolate and characterise the mucilage from the aerial parts of C. halicacabum. The isolated mucilage was characterised for physical, chemical and flow properties. The mucilage was further characterised by Fourier transform infrared (FTIR) spectroscopy. The isolated mucilage had good physical, chemical and flow properties. The FTIR spectrum of mucilage showed characteristic peaks. It was concluded that the C. halicacabum mucilage can be used as an excipient in pharmaceutical formulations.
Key words: Cardiospermum halicacabum, characterisation, isolation, mucilage

Full Text:

PDF

References


Jain GK, Shah DP, Prajapati VD, Jain VC. Gums and mucilages:

Versatile excipients for pharmaceutical formulations. Asian J

Pharm Sci 2009;4:309‑23.

Bodempudi S, Deveswaran R, Bharath S, Basavaraj BV, Madhavan

V. Studies on Vigna mungo mucilage as a pharmaceuctical excipient.

J Chem Pharm Res 2011;3:118‑25.

Jain GK, Shah DP, Jain VC, Patel MJ, Vithalani DA. Evaluating

mucilage from Aloe Barbadensis Miller as Pharmaceutical excipient

for sustained release matrix tablets. Pharm Technol 2007:31:90‑8.

Jain GK, Shah DP. Assessing Hibiscus rosasinensis Linn as an

excipient in sustained release tablets. Pharm Technol 2008;32:62.

Krithikar KR, Basu BD. Indian Medicinal Plants. 2nd ed. Dehradun,

India: International Book Distributors; 1999.

Anonymus. The wealth of India, First supplement series (Raw

materials). Vol. 3. New Delhi, India: National Institute of Science

and communication, CSIR; 2003.

Pawar H, Mello PM. Isolation of seed gum from Cassia tora and

preliminary studies of its application as a binder for tablets. Indian

Drugs 2004;41:465‑8.

Ramu G, Krishna Mohan G, Jayaveera KN. Preliminary

investigation of Patchaippasali mucilage (Basella alba) as tablet

binder. Int J Green Pharm 2011;5:24‑7.

Indian Pharmacopeia. Ministry of Health and family welfare.

Government of India. New Delhi. New Delhi: Controller of

Publications: 1996. p. A54.

Tripathi SS, Porwal A, Tiwari V, Sharma UK. Isolation and

Characterisation of mucilage obtained from Abutilon indicum leaf

and seed. J Pharm Res 2011;4:1414‑6.

Bharadia PD, Patel MM, Patel GC, Patel GN. l. A Preliminary

Investigation on Sesbania gum as a pharmaceutical excipient. Int

J Pharma Excip 2004;1:99‑102.

Sink PJ, Martin’s. Physical Pharmacy and Pharmaceutical sciences.

th ed. New Delhi: B.I Publications Pvt. Ltd; 2006.

Sharma YR., Elementary organic spectroscopy. Principles

and chemical applications. New Delhi: S Chand and Co. Ltd;

Chatwal GR, Anand SK. Instrumental Methods of Analysis.

Mumbai: Himalaya Publishing House; 2004.




DOI: http://dx.doi.org/10.22377/ijgp.v5i4.220

Refbacks

  • There are currently no refbacks.