Wound-healing potential of aqueous and ethanolic extracts of apamarga leaves

P. K. Ghosh; V. B. Gupta; M. S. Rathore; Iqbal Hussain

doi:10.22377/ijgp.v5i1.167

Wound-healing potential of aqueous and ethanolic extracts of apamarga leaves

P. K. Ghosh, V. B. Gupta, M. S. Rathore, Iqbal Hussain

Abstract

The present research work was aimed at exploring the wound-healing activity of alcoholic and an aqueous Achyranthes aspera Linn (apamarga) leaf extract. Leaf extracts (aqueous and ethanolic) were examined for its wound-healing activity in the form of ointment (1% w/w) in Excision model and Incision model in rats. The evaluation was made in terms of wound contractibility and wound closure time. A. aspera Linn leaf extract showed significant (P<0.001) wound-healing activity when compared with control and was as effective as soframycin (standard cream for comparison). The wound-healing potential of ethanolic extract was slightly more compared with aqueous extract. The present study showed the wound-healing potential of apamarga leaves.
Key words: Apamarga, extract, wound

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DOI: https://doi.org/10.22377/ijgp.v5i1.167

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